Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL9250109

NC(=O)C1CNCCN1CC(=O)Nc1c(Cl)cc(N)cc1Cl.O=C(O)C(F)(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 1/20 0.52
F2 P00734 1/20 0.36
F9 P00740 1/20 0.36
F10 P00742 1/20 0.36
F12 P00748 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
F7 P08709 1/20 0.36
PRSS3 P35030 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ALDH1A1 P00352 3/20 0.34
SLC2A1 P11166 1/20 0.34
FPR2 P25090 1/20 0.32
SCN9A Q15858 1/20 0.32
ACHE P22303 1/20 0.32
DRD4 P21917 1/20 0.31
KDM4E B2RXH2 2/20 0.30
MAPT P10636 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL8553848 0.81 NPC1 (0.50) SLC29A1NPC1RAB9AALDH1A1SLC2A1
SCHEMBL10680876 0.73 ALDH1A1 (0.43) ALDH1A1DRD4KDM4EMAPTTSHR
SCHEMBL9253269 0.72 SLC29A1 (0.52) SLC29A1NPC1RAB9AALDH1A1KDM4E
Draflazine SCHEMBL215826 0.69 SLC29A1 (1.00) SLC29A1RAB9ADRD4HTR2CTSHR
Draflazine SCHEMBL7705425 0.69 SLC29A1 (1.00) SLC29A1RAB9ADRD4HTR2CTSHR
SCHEMBL9029426 0.68 ALDH1A1 (0.44) NPC1RAB9AALDH1A1DRD4KDM4E
Draflazine SCHEMBL9410932 0.68 SLC29A1 (0.98) SLC29A1RAB9ADRD4HTR2CTSHR
Draflazine SCHEMBL9362256 0.68 SLC29A1 (0.98) SLC29A1RAB9ADRD4HTR2CTSHR
SCHEMBL9031073 0.66 NPC1 (0.56) NPC1RAB9AALDH1A1DRD4KDM4E
Hydrochloric Acid SCHEMBL9808242 0.65 SLC29A1 (0.86) SLC29A1RAB9ADRD4HTR2CTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5382584-A Antiischemic agents BRISTOL-MYERS SQUIBB COMPANY (US) 1995-01-17 US disclosed