Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42119 | 0.92 | OPRM1 (0.59) | KCNH2CYP2D6KMT2AOPRM1CHRM2 | |
| SCHEMBL9257134 | 0.85 | OPRM1 (0.54) | KCNH2CYP2D6OPRM1CHRM2ADRA2A | |
| SCHEMBL9250914 | 0.85 | OPRM1 (0.54) | KCNH2CYP2D6KMT2AOPRM1CHRM2 | |
| SCHEMBL9258075 | 0.85 | OPRM1 (0.54) | KCNH2CYP2D6KMT2AOPRM1CHRM2 | |
| SCHEMBL9258410 | 0.82 | OPRM1 (0.56) | KCNH2CYP2D6KMT2AOPRM1CHRM2 | |
| SCHEMBL9252844 | 0.82 | OPRM1 (0.57) | KCNH2CYP2D6KMT2AOPRM1CHRM2 | |
| SCHEMBL9256149 | 0.82 | OPRM1 (0.55) | KCNH2CYP2D6KMT2AOPRM1CHRM2 | |
| SCHEMBL1381608 | 0.82 | DRD3 (0.66) | KCNH2CYP2D6KMT2AOPRM1CHRM2 | |
| SCHEMBL2054235 | 0.82 | CYP2D6 (0.67) | KCNH2CYP2D6KMT2AOPRM1CHRM2 | |
| SCHEMBL1502253 | 0.82 | CYP2D6 (0.65) | KCNH2CYP2D6KMT2AOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |