Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250184 | 1.00 | TBXAS1 (0.42) | TBXAS1TBXA2RCYP2B6SMN1; SMN2HTT | |
| SCHEMBL9247777 | 0.81 | TBXAS1 (0.46) | TBXAS1TBXA2RCYP2B6SMN1; SMN2HTT | |
| SCHEMBL9247773 | 0.81 | TBXAS1 (0.46) | TBXAS1TBXA2RCYP2B6SMN1; SMN2HTT | |
| SCHEMBL9241749 | 0.81 | GBA1 (0.34) | GBA1 | |
| SCHEMBL9241744 | 0.81 | GBA1 (0.34) | GBA1 | |
| SCHEMBL9250010 | 0.78 | TBXAS1 (0.39) | TBXAS1TBXA2RCYP2B6SMN1; SMN2HTT | |
| SCHEMBL9244414 | 0.76 | TBXAS1 (0.40) | TBXAS1CYP2B6CYP11B1CYP11B2 | |
| SCHEMBL9246756 | 0.76 | TBXAS1 (0.40) | TBXAS1CYP2B6CYP11B1CYP11B2 | |
| SCHEMBL9246754 | 0.76 | TBXAS1 (0.40) | TBXAS1CYP2B6CYP11B1CYP11B2 | |
| SCHEMBL9244435 | 0.76 | TBXAS1 (0.40) | TBXAS1CYP2B6CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449785-A | Fungicides with triazole groups | HOFFMANN-LA ROCHE INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | disclosed |