Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252296 | 0.91 | ACE (0.59) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9254552 | 0.89 | ACE (0.51) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9256899 | 0.84 | ACE (0.42) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9250644 | 0.81 | ACE (0.46) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9259678 | 0.81 | ACE (0.46) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9251897 | 0.80 | ACE (0.47) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9255126 | 0.79 | ACE (0.46) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL11021440 | 0.79 | ACE (0.55) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL10700347 | 0.79 | ACE (0.55) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9257149 | 0.79 | ACE (0.45) | ACEMEN1KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401766-A | Hypotensive agents with vasodilation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| US-5162362-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5158959-A | Treatment of hypertension | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |