Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031952 | 0.82 | ELANE (0.47) | ELANEATML3MBTL1MAPTTDP1 | |
| SCHEMBL3179425 | 0.82 | ELANE (0.47) | ELANEATML3MBTL1MAPTTDP1 | |
| SCHEMBL131278 | 0.81 | ELANE (0.51) | ELANEATML3MBTL1MAPTTDP1 | |
| SCHEMBL539078 | 0.81 | ELANE (0.50) | ELANEATML3MBTL1MAPTTDP1 | |
| SCHEMBL26453070 | 0.81 | ELANE (0.50) | ELANEATML3MBTL1MAPTTDP1 | |
| SCHEMBL7943217 | 0.81 | ELANE (0.46) | ELANEATML3MBTL1MAPTTDP1 | |
| Ammonia Solution, Strong SCHEMBL27373723 | 0.81 | ELANE (0.46) | ELANEATML3MBTL1MAPTTDP1 | |
| SCHEMBL7942646 | 0.79 | ELANE (0.49) | ELANEATML3MBTL1MAPTTDP1 | |
| SCHEMBL9486142 | 0.79 | ELANE (0.45) | ELANEATML3MBTL1MAPTTDP1 | |
| SCHEMBL6487373 | 0.79 | ELANE (0.45) | ELANEATML3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401766-A | Hypotensive agents with vasodilation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| US-5162362-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5158959-A | Treatment of hypertension | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |