SCHEMBL9486142

SCHEMBL9486142

CCC(Cl)(Cl)C(=O)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 10/20 0.45
ATM Q13315 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
GAA P10253 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
ALOX15 P16050 2/20 0.38
RAB9A P51151 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27379292 0.86 ELANE (0.47) ELANEATML3MBTL1MAPTMEN1
SCHEMBL11651356 0.85 ELANE (0.40) ELANEATML3MBTL1MAPTMEN1
SCHEMBL10584548 0.84 ELANE (0.47) ELANEATML3MBTL1MAPTMEN1
SCHEMBL26453070 0.83 ELANE (0.50) ELANEATML3MBTL1MAPTTDP1
SCHEMBL8031952 0.81 ELANE (0.47) ELANEATML3MBTL1MAPTTDP1
SCHEMBL3179425 0.81 ELANE (0.47) ELANEATML3MBTL1MAPTTDP1
SCHEMBL539078 0.79 ELANE (0.50) ELANEATML3MBTL1MAPTTDP1
SCHEMBL7943217 0.79 ELANE (0.46) ELANEATML3MBTL1MAPTTDP1
Ammonia Solution, Strong SCHEMBL27373723 0.79 ELANE (0.46) ELANEATML3MBTL1MAPTTDP1
SCHEMBL9250267 0.79 ELANE (0.46) ELANEATML3MBTL1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1709920-A Amido complexes of vanadium for olefin polymerization LANXESS DEUTSCHLAND GMBH (DE) 2005-12-21 CN claimed
CN-1709920-A Amido complexes of vanadium for olefin polymerization LANXESS DEUTSCHLAND GMBH (DE) 2005-12-21 CN disclosed
US-5210160-A PREPARATION OF HOMOPOLYMERS OF ETHENE AND COPOLYMERS OF ETHENE WITH HIGHER A-MONOOLEFINS USING A ZIEGLER CATALYST SYSTEM BASF AKTIENGESELLSCHAFT (DE) 1993-05-11 US disclosed