Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250344 | 1.00 | MAOB (0.37) | MAOBMAOAGPR84RARBCNR1 | |
| SCHEMBL9766729 | 0.98 | MAOB (0.36) | MAOBMAOAGPR84RARBCNR1 | |
| SCHEMBL9244220 | 0.96 | MAOB (0.36) | MAOBMAOAGPR84RARBCNR1 | |
| SCHEMBL9244214 | 0.96 | MAOB (0.36) | MAOBMAOAGPR84RARBCNR1 | |
| SCHEMBL9250244 | 0.95 | RARB (0.38) | MAOBMAOAGPR84RARBCNR1 | |
| SCHEMBL9250250 | 0.95 | RARB (0.38) | MAOBMAOAGPR84RARBCNR1 | |
| SCHEMBL9249924 | 0.92 | MAOB (0.39) | MAOBMAOAGPR84RARBCNR1 | |
| SCHEMBL9249918 | 0.92 | MAOB (0.39) | MAOBMAOAGPR84RARBCNR1 | |
| SCHEMBL9253045 | 0.90 | MAOB (0.36) | MAOBMAOAGPR84CNR1 | |
| SCHEMBL9253048 | 0.90 | MAOB (0.36) | MAOBMAOAGPR84CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |