Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253048 | 1.00 | MAOB (0.36) | MAOBMAOACNR1GPR84FFAR4 | |
| SCHEMBL9249924 | 0.92 | MAOB (0.39) | MAOBMAOACNR1GPR84FFAR4 | |
| SCHEMBL9249918 | 0.92 | MAOB (0.39) | MAOBMAOACNR1GPR84FFAR4 | |
| SCHEMBL9250338 | 0.90 | MAOB (0.37) | MAOBMAOACNR1GPR84 | |
| SCHEMBL9250344 | 0.90 | MAOB (0.37) | MAOBMAOACNR1GPR84 | |
| SCHEMBL9244220 | 0.89 | MAOB (0.36) | MAOBMAOACNR1GPR84 | |
| SCHEMBL9244214 | 0.89 | MAOB (0.36) | MAOBMAOACNR1GPR84 | |
| SCHEMBL9250250 | 0.88 | RARB (0.38) | MAOBMAOACNR1GPR84 | |
| SCHEMBL9766729 | 0.88 | MAOB (0.36) | MAOBMAOACNR1GPR84 | |
| SCHEMBL9250244 | 0.88 | RARB (0.38) | MAOBMAOACNR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |