SCHEMBL9250397

SCHEMBL9250397

OCC[C@@H](O)c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.50
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 2/20 0.44
SIGMAR1 Q99720 5/20 0.42
DRD2 P14416 4/20 0.42
DRD3 P35462 2/20 0.42
LMNA P02545 1/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2C9 P11712 1/20 0.42
HTR1A P08908 1/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3183272 1.00 AOC3 (0.50) AOC3MEN1KMT2AKDM4ESIGMAR1
SCHEMBL9246291 1.00 AOC3 (0.50) AOC3MEN1KMT2AKDM4ESIGMAR1
SCHEMBL13786083 0.89 AOC3 (0.48) AOC3MEN1KMT2AKDM4ESIGMAR1
SCHEMBL13786104 0.89 AOC3 (0.48) AOC3MEN1KMT2AKDM4ESIGMAR1
SCHEMBL24228682 0.87 AOC3 (0.47) AOC3MEN1KMT2AKDM4ESIGMAR1
SCHEMBL31489731 0.82 AOC3 (0.50) AOC3MEN1KMT2AKDM4ESIGMAR1
SCHEMBL16340559 0.81 AOC3 (0.53) AOC3MEN1KMT2AKDM4ECYP3A4
SCHEMBL6481591 0.81 AOC3 (0.53) AOC3MEN1KMT2AKDM4ECYP3A4
SCHEMBL1155019 0.81 AOC3 (0.53) AOC3MEN1KMT2AKDM4ECYP3A4
SCHEMBL22473432 0.81 TRPA1 (0.47) AOC3MEN1KMT2AKDM4ESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5395983-A Process for producing 1-phenyl-1,3-propanediols having high optical purtiy CHISSO CORPORATION (JP) 1995-03-07 US disclosed