Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252559 | 0.92 | ALOX5 (0.44) | ALOX5PTGS1 | |
| SCHEMBL9255208 | 0.88 | ALOX5 (0.47) | ALOX5PTGS1 | |
| SCHEMBL9037267 | 0.84 | ALOX5 (0.44) | ALOX5PTGS1 | |
| SCHEMBL9036639 | 0.83 | ALOX5 (0.46) | ALOX5PTGS1 | |
| SCHEMBL9301044 | 0.82 | ALOX5 (0.47) | ALOX5PTGS1 | |
| SCHEMBL9047341 | 0.82 | ALOX5 (0.43) | ALOX5PTGS1 | |
| SCHEMBL9212956 | 0.82 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL9035202 | 0.82 | ALOX5 (0.43) | ALOX5PTGS1 | |
| SCHEMBL9049483 | 0.82 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL9300461 | 0.82 | ALOX5 (0.47) | ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334614-A | Lipoxygenase inhibitor | ZENECA LTD. (GB) | 1994-08-02 | — | — | US | claimed |
| US-5453439-A | Antiinflammatory agent, antiallergen; lipoxygenase inhibitor | ZENECA LIMITED (GB) | 1995-09-26 | — | — | US | disclosed |
| US-5334614-A | Lipoxygenase inhibitor | ZENECA LTD. (GB) | 1994-08-02 | — | — | US | disclosed |