Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250475 | 1.00 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9250481 | 1.00 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9480546 | 1.00 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9481233 | 0.92 | SGPL1 (0.36) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9319900 | 0.92 | SGPL1 (0.36) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9481226 | 0.92 | SGPL1 (0.36) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9319888 | 0.92 | SGPL1 (0.36) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9481464 | 0.91 | L3MBTL1 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9481500 | 0.91 | L3MBTL1 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9481490 | 0.91 | L3MBTL1 (0.34) | USP5HDAC6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-5185098-A | Liquid crystalline mixtures containing 3,4-difluorophenyl-substituted bicyclohexyls | HOFFMANN-LA ROCHE INC. (US) | 1993-02-09 | — | — | US | disclosed |