Toluene

Toluene

SCHEMBL9250593

CCCCCCc1ccc(C)c(CCCCCC)c1.Cc1ccccc1.Cc1ccccc1.Cc1ccccc1.Cc1ccccc1.Cc1ccccc1.Cc1ccccc1.Cc1ccccc1.Cc1ccccc1.Cc1ccccc1

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.49
MAPT P10636 3/20 0.46
HTT P42858 3/20 0.46
RAD52 P43351 2/20 0.46
MAPK1 P28482 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
APAF1 O14727 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
BLM P54132 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HTR2A P28223 1/20 0.44
THRB P10828 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KAT8 Q9H7Z6 2/20 0.43
HSD11B1 P28845 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL5182600 1.00 GPR3 (0.49) GPR3MAPTHTTRAD52MAPK1
Toluene SCHEMBL2493000 1.00 GPR3 (0.49) GPR3MAPTHTTRAD52MAPK1
Toluene SCHEMBL15639860 1.00 GPR3 (0.49) GPR3MAPTHTTRAD52MAPK1
SCHEMBL10601286 0.90 ESR1 (0.50) GPR3MAPTHTTRAD52MAPK1
SCHEMBL8932621 0.90 ESR1 (0.50) GPR3MAPTHTTRAD52MAPK1
SCHEMBL2071234 0.90 ESR1 (0.50) GPR3MAPTHTTRAD52MAPK1
SCHEMBL1413328 0.90 ESR1 (0.50) GPR3MAPTHTTRAD52MAPK1
SCHEMBL18260106 0.90 ESR1 (0.50) GPR3MAPTHTTRAD52MAPK1
SCHEMBL7169112 0.88 SKP2 (0.52) GPR3MAPTHTTRAD52MAPK1
Toluene SCHEMBL9422293 0.84 BCHE (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458320-B1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1995-01-04 EP disclosed
US-5188762-A Ferroelectric liquid crystal with high response speed and small temperature dependence CANON KABUSHIKI KAISHA (JP) 1993-02-23 US disclosed
EP-0458320-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1991-11-27 EP disclosed