SCHEMBL9250671

SCHEMBL9250671

O=C(CN1CCc2ccccc21)Nc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.68
MAPT P10636 6/20 0.68
MAPK1 P28482 2/20 0.68
MEN1 O00255 6/20 0.67
KMT2A Q03164 6/20 0.67
POLB P06746 2/20 0.67
NPC1 O15118 3/20 0.65
RAB9A P51151 2/20 0.65
CHRM2 P08172 1/20 0.64
CHRM4 P08173 1/20 0.64
CHRM1 P11229 1/20 0.64
CHRM3 P20309 1/20 0.64
HSD17B10 Q99714 1/20 0.61
HTT P42858 1/20 0.61
GAA P10253 3/20 0.61
TP53 P04637 1/20 0.58
PKM P14618 1/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21466987 0.86 CHRM2 (0.85) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL20246753 0.86 ALDH1A1 (0.61) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL17175806 0.85 KMT2A (0.87) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL10154068 0.82 ALDH1A1 (0.65) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL5152882 0.81 MEN1 (0.71) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL8186278 0.78 MAPT (0.80) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL21467003 0.78 ALDH1A1 (0.54) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL28638610 0.78 CHRM2 (1.00) MAPTMEN1KMT2APOLBCHRM2
SCHEMBL22560809 0.78 ALDH1A1 (0.54) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL18715213 0.78 NPC1 (0.53) ALDH1A1MAPTMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5474880-A Pyrrolazole type cyan coupler and phenol or amide type high boiling solvent; high color formability and excellent color reproductibility FUJI PHOTO FILM CO., LTD. (JP) 1995-12-12 US disclosed
US-5370978-A Reduction of stain generation in white area on storage FUJI PHOTO FILM CO., LTD. (JP) 1994-12-06 US disclosed