Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530700 | 0.93 | TSHR (0.48) | TSHRHPGDALDH1A1HCAR2NAAA | |
| SCHEMBL971536 | 0.92 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL9246482 | 0.87 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL9776516 | 0.85 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acetic Acid SCHEMBL7449617 | 0.85 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL1245965 | 0.85 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL9249626 | 0.84 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL978390 | 0.84 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid SCHEMBL11282593 | 0.83 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Ethyl Ester SCHEMBL3630809 | 0.83 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393529-A | Sustained release | LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG (DE) | 1995-02-28 | — | — | US | disclosed |