Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250677 | 0.93 | TSHR (0.47) | TSHRNAAAHCAR2FAAHALDH1A1 | |
| SCHEMBL1245965 | 0.91 | TSHR (0.57) | TSHRNAAAHCAR2FAAHALDH1A1 | |
| Acrylic Acid SCHEMBL11282593 | 0.86 | TSHR (0.49) | TSHRNAAAHCAR2FAAHALDH1A1 | |
| SCHEMBL971536 | 0.84 | TSHR (0.55) | TSHRNAAAHCAR2ALDH1A1HPGD | |
| SCHEMBL6048367 | 0.82 | TSHR (0.57) | TSHRNAAAHCAR2FAAHALDH1A1 | |
| SCHEMBL9249626 | 0.81 | TSHR (0.46) | TSHRNAAAHCAR2ALDH1A1HPGD | |
| Vinyl Chloride SCHEMBL9467848 | 0.80 | TSHR (0.45) | TSHRNAAAHCAR2ALDH1A1HPGD | |
| SCHEMBL7912871 | 0.80 | FAAH (0.47) | TSHRFAAHALDH1A1HPGDTDP1 | |
| SCHEMBL28149809 | 0.80 | TSHR (0.75) | TSHRNAAAHCAR2FAAHALDH1A1 | |
| SCHEMBL28471522 | 0.80 | TSHR (0.75) | TSHRNAAAHCAR2FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383149-B2 | High enhancer-loading polyacrylate formulation for transdermal applications | ALZA CORPORATION (US) | 2013-02-26 | — | — | US | disclosed |
| US-20070098771-A1 | High enhancer-loading polyacrylate formulation for transdermal applications | ALZA CORPORATION | 2007-05-03 | — | — | US | disclosed |
| US-5393529-A | Sustained release | LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG (DE) | 1995-02-28 | — | — | US | disclosed |