SCHEMBL9250696

SCHEMBL9250696

CC(C)(C)c1ccc(CCO)c(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.42
CYP2C19 P33261 3/20 0.42
ALDH1A1 P00352 3/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP2D6 P10635 3/20 0.40
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.35
TYR P14679 1/20 0.35
KLF10 Q13118 1/20 0.35
HTR1D P28221 5/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10442609 0.88 CYP1A2 (0.47) CYP1A2CYP2C19ALDH1A1HPGDALOX15
SCHEMBL1447610 0.86 KLF10 (0.47) CYP1A2CYP2C19ALDH1A1HPGDALOX15
SCHEMBL15800261 0.82 HTR1D (0.44) CYP1A2CYP2C19ALDH1A1HPGDALOX15
SCHEMBL31222192 0.81 CYP1A2 (0.40) CYP1A2CYP2C19ALDH1A1HPGDALOX15
SCHEMBL9251352 0.81 CYP2C19 (0.42) CYP1A2CYP2C19ALDH1A1HPGDALOX15
SCHEMBL2582081 0.79 CYP2C19 (0.47) CYP1A2CYP2C19ALDH1A1HPGDALOX15
SCHEMBL19222193 0.79 CYP2D6 (0.42) CYP1A2CYP2C19ALDH1A1HPGDALOX15
SCHEMBL29040644 0.79 NR1H4 (0.52) CYP2C19ALDH1A1CYP3A4
SCHEMBL9259677 0.78 CYP2C19 (0.40) CYP1A2CYP2C19ALDH1A1HPGDALOX15
SCHEMBL944498 0.78 CYP2C19 (0.46) CYP1A2CYP2C19ALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5420343-A ANTIINFLAMMATORY AGENTS; CYCLOOXYGENASE INHIBITORS G. D. SEARLE & CO. (US) 1995-05-30 US disclosed