SCHEMBL9250813

SCHEMBL9250813

O=C(O)c1cc(-c2ccccc2)cc(Cc2ccccc2)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 9/20 1.00
PTPN2 P17706 3/20 0.84
PTPN6 P29350 3/20 0.84
AKR1C2 P52895 3/20 0.57
AKR1C1 Q04828 3/20 0.57
AKR1C4 P17516 1/20 0.57
AKR1C3 P42330 1/20 0.57
ACMSD Q8TDX5 2/20 0.54
HNF4A P41235 2/20 0.49
HMGB1 P09429 1/20 0.49
CXCL12 P48061 1/20 0.49
DHFR P00374 1/20 0.49
MCL1 Q07820 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599389 0.85 PTPN1 (0.80) PTPN1PTPN2PTPN6AKR1C2AKR1C1
SCHEMBL10873237 0.84 PTPN1 (0.72) PTPN1PTPN2PTPN6
SCHEMBL3714683 0.83 PTPN1 (0.76) PTPN1PTPN2PTPN6HNF4AHMGB1
SCHEMBL5444611 0.83 PTPN1 (1.00) PTPN1PTPN2PTPN6ACMSDHNF4A
SCHEMBL29236440 0.82 PTPN1 (0.97) PTPN1PTPN2PTPN6ACMSDHNF4A
SCHEMBL28707306 0.81 PTPN1 (0.73) PTPN1PTPN2PTPN6HNF4AHMGB1
SCHEMBL11693142 0.81 PTPN1 (0.67) PTPN1PTPN2PTPN6AKR1C2AKR1C1
SCHEMBL12922967 0.81 PTPN1 (0.67) PTPN1PTPN2PTPN6
SCHEMBL9615384 0.81 PTPN1 (0.88) PTPN1PTPN2PTPN6HNF4AHMGB1
SCHEMBL17774718 0.81 PTPN1 (0.71) PTPN1PTPN2PTPN6HNF4AHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 EP disclosed
US-5141557-A Mixture of benzoic acid salt, anionic surfactant, and novolak phenolic resin BROTHER KOGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed
US-3983292-A Pressure sensitive recording papers SANKO CHEMICAL COMPANY LTD. (JA) 1976-09-28 US disclosed