Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.67 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.57 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11693510 | 0.85 | AKR1C2 (0.52) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL9250813 | 0.81 | PTPN1 (1.00) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL11693280 | 0.81 | AKR1C2 (0.66) | AKR1C2AKR1C1RPA1 | |
| SCHEMBL9251915 | 0.79 | HPGD (0.75) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL11695681 | 0.77 | AKR1C2 (0.58) | AKR1C2AKR1C1RPA1 | |
| SCHEMBL11692722 | 0.77 | AKR1C2 (0.59) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL3979148 | 0.74 | ACMSD (0.59) | ALDH1A1HPGDHSD17B10ACMSDRPA1 | |
| SCHEMBL16608990 | 0.74 | RPA1 (0.58) | ALDH1A1RPA1 | |
| SCHEMBL10724258 | 0.73 | PTPN1 (0.67) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL5444611 | 0.72 | PTPN1 (1.00) | PTPN1PTPN2PTPN6ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044049-A | Phenyl benzoic acid compounds | MERCK & CO., INC. (US) | 1977-08-23 | — | — | US | disclosed |