Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246989 | 0.89 | PDE2A (0.32) | CYP2C9TSHRSLC6A2CYP2C19HTT | |
| SCHEMBL8830792 | 0.82 | TACR1 (0.43) | TACR1TACR3SLC6A2HTTMAPT | |
| SCHEMBL9253910 | 0.76 | TACR3 (0.40) | TACR1TACR3TSHRSLC6A2HTT | |
| SCHEMBL9169837 | 0.75 | TSHR (0.43) | CYP2C9TACR1TACR3TSHRCYP2C19 | |
| SCHEMBL9254143 | 0.73 | TACR1 (0.32) | TACR1TACR3TSHRCYP2C19MAPT | |
| SCHEMBL4809720 | 0.71 | TACR1 (0.55) | CYP2C9TACR1TACR3TSHRCYP2C19 | |
| SCHEMBL8830812 | 0.70 | TACR1 (0.45) | CYP2C9TACR1TACR3TSHRCYP2C19 | |
| SCHEMBL8830873 | 0.70 | NR1H4 (0.36) | TSHRSLC6A2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL22211342 | 0.69 | TACR1 (0.44) | CYP2C9TACR1TACR3TSHRCYP2C19 | |
| SCHEMBL2039023 | 0.69 | TACR1 (0.44) | TACR1TACR3SLC6A2CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420343-A | ANTIINFLAMMATORY AGENTS; CYCLOOXYGENASE INHIBITORS | G. D. SEARLE & CO. (US) | 1995-05-30 | — | — | US | disclosed |