Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2039023 | 0.89 | TACR1 (0.44) | TACR1TACR3CYP2C19MAPTPOLB | |
| SCHEMBL8830812 | 0.88 | TACR1 (0.45) | TACR1TACR3CYP2C19GPR119MAPT | |
| SCHEMBL9168218 | 0.86 | TACR1 (0.44) | TACR1TACR3CYP2C19GPR119MAPT | |
| SCHEMBL4809720 | 0.86 | TACR1 (0.55) | TACR1TACR3CYP2C19GPR119MAPT | |
| SCHEMBL9363274 | 0.85 | TACR1 (0.44) | TACR1TACR3MAPTPOLBNPC1 | |
| SCHEMBL26679406 | 0.85 | TACR3 (0.57) | TACR1TACR3CYP2C19GPR119MAPT | |
| SCHEMBL8830633 | 0.84 | TACR1 (0.51) | TACR1TACR3CYP2C19GPR119MAPT | |
| SCHEMBL8830792 | 0.84 | TACR1 (0.43) | TACR1TACR3GPR119MAPTRECQL | |
| SCHEMBL22211320 | 0.83 | TACR1 (0.42) | TACR1TACR3CYP2C19GPR119MAPT | |
| SCHEMBL8830648 | 0.83 | GPR119 (0.45) | TACR1TACR3CYP2C19GPR119CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210078941-A1 | Method For Preparing Substituted Phenylacetic Acid Derivative | JIANGSU RUIKE MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2021-03-18 | — | — | US | disclosed |
| EP-3680227-A1 | METHOD FOR PREPARING SUBSTITUTED PHENYLACETIC ACID DERIVATIVE | Jiangsu Ruike Medical Science And Technology Co., Ltd. (CN) | 2020-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078941-A1 | Method For Preparing Substituted Phenylacetic Acid Derivative | ALOX5, LOXL4, CYP3A5 | TACR1 919/4885TACR3 1262/4885CYP2C19 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.