Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506778 | 0.81 | PTPN11 (0.52) | NPC1RAB9APTPN11PLAUCES2 | |
| SCHEMBL9506785 | 0.81 | PTPN11 (0.52) | NPC1RAB9APTPN11PLAUCES2 | |
| SCHEMBL8081716 | 0.79 | MEN1 (0.60) | NPC1RAB9APTPN11PLAUCYP1A2 | |
| SCHEMBL9177007 | 0.79 | MEN1 (0.60) | NPC1RAB9APTPN11PLAUCYP1A2 | |
| SCHEMBL2327506 | 0.76 | BACE1 (0.45) | CES2HPGDALDH1A1MAPTNPSR1 | |
| SCHEMBL9152781 | 0.76 | CA1 (0.52) | NPC1RAB9APTPN11PLAUCES2 | |
| SCHEMBL9152771 | 0.76 | CA1 (0.52) | NPC1RAB9APTPN11PLAUCES2 | |
| SCHEMBL11217415 | 0.75 | IDE (0.53) | NPC1RAB9APTPN11PLAUCYP1A2 | |
| SCHEMBL24213305 | 0.73 | NPC1 (0.59) | NPC1RAB9APTPN11PLAUCES2 | |
| SCHEMBL5838349 | 0.73 | NPC1 (0.59) | NPC1RAB9APTPN11PLAUCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625971-A4 | UV LIGHT STABILIZING, ANTIOXIDANT AND COLORANT COMPOUNDS. | — | 1995-01-04 | — | — | EP | disclosed |
| EP-0625971-A1 | UV LIGHT STABILIZING, ANTIOXIDANT AND COLORANT COMPOUNDS | HOECHST CELANESE CORPORATION (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993015063-A1 | UV LIGHT STABILIZING, ANTIOXIDANT AND COLORANT COMPOUNDS | HOECHST CELANESE CORPORATION (US) | 1993-08-05 | — | — | WO | disclosed |