Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.61 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258410 | 0.94 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1CYP19A1 | |
| SCHEMBL9257361 | 0.91 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1CYP19A1 | |
| SCHEMBL9252838 | 0.81 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL9251268 | 0.80 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL42119 | 0.80 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL9254374 | 0.78 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL9256147 | 0.78 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL9257134 | 0.77 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL8672898 | 0.76 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1CYP19A1 | |
| SCHEMBL2201461 | 0.75 | OPRM1 (0.41) | OPRM1OPRD1OPRK1OPRL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |