Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 13/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9243493 | 0.88 | USP7 (0.47) | USP7ESR2ESR1ALOX5PDE4A | |
| SCHEMBL8926006 | 0.81 | ESR1 (0.57) | USP7ESR2ESR1ALOX5PDE4A | |
| SCHEMBL30234292 | 0.80 | ESR2 (0.53) | USP7ESR2ESR1ALOX5PDE4A | |
| SCHEMBL2201812 | 0.80 | ESR2 (0.53) | USP7ESR2ESR1ALOX5PDE4A | |
| SCHEMBL7105505 | 0.79 | ESR1 (0.47) | USP7ESR2ESR1ALOX5 | |
| SCHEMBL7102146 | 0.79 | ESR2 (0.57) | ESR2ESR1ALOX5PDE4APDE4B | |
| SCHEMBL9396340 | 0.79 | ESR2 (0.57) | ESR2ESR1ALOX5PDE4APDE4B | |
| SCHEMBL29531437 | 0.79 | ESR2 (0.57) | ESR2ESR1ALOX5PDE4APDE4B | |
| SCHEMBL9794424 | 0.79 | PDE4A (0.57) | ESR2ESR1ALOX5PDE4APDE4B | |
| SCHEMBL2139881 | 0.79 | ESR2 (0.57) | ESR2ESR1ALOX5PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923955-A | Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene | MONTEDISON S.P.A. (IT) | 1990-05-08 | — | — | US | claimed |
| EP-0321107-B1 | Thermotropic liquid-crystalline aromatic polyesters | HIMONT ITALIA (IT) | 1995-01-25 | — | — | EP | disclosed |
| US-4923955-A | Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene | MONTEDISON S.P.A. (IT) | 1990-05-08 | — | — | US | disclosed |
| EP-0321107-A1 | Thermotropic liquid-crystalline aromatic polyesters | HIMONT ITALIA S.r.l. (IT) | 1989-06-21 | — | — | EP | disclosed |