SCHEMBL9251498

SCHEMBL9251498

CCOCCOC(=O)C(Br)(Br)Br

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
TSHR P16473 2/20 0.56
THRB P10828 2/20 0.48
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TRPA1 O75762 1/20 0.33
HSD17B10 Q99714 2/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14361863 0.86 ALDH1A1 (0.41) ALDH1A1TSHRTHRBHSD17B10
SCHEMBL14269371 0.86 ALDH1A1 (0.41) ALDH1A1TSHRTHRBHSD17B10
SCHEMBL8137603 0.80 ALDH1A1 (0.58) ALDH1A1TSHRTHRBSMN1; SMN2HSD17B10
SCHEMBL9419509 0.79 ALDH1A1 (0.43) ALDH1A1TSHRRAB9ASMN1; SMN2POLB
SCHEMBL297524 0.79
SCHEMBL9254594 0.78 ALDH1A1 (0.56) ALDH1A1TSHRTHRBSMN1; SMN2HSD17B10
SCHEMBL20012793 0.78 ALDH1A1 (0.56) ALDH1A1TSHRTHRBSMN1; SMN2HSD17B10
SCHEMBL16021740 0.78 ALDH1A1 (0.56) ALDH1A1TSHRTHRBSMN1; SMN2HSD17B10
SCHEMBL9937107 0.78 ALDH1A1 (0.56) ALDH1A1TSHRTHRBNPC1HPGD
SCHEMBL22115779 0.77 ALDH1A1 (0.54) ALDH1A1TSHRTHRBSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5401427-A Depolymerized ethylene-propylene copolymer, additive for lubricants EXXON CHEMICAL PATENTS INC. (US) 1995-03-28 US disclosed
US-5348673-A Multifunctional viscosity index improver derived from amido-amine and degraded ethylene copolymer exhibiting improved low temperature viscometric properties EXXON CHEMICAL PATENTS INC. (US) 1994-09-20 US disclosed
EP-0422859-B1 Process for preparing a viscosity index improver EXXON CHEMICAL PATENTS INC (US) 1994-07-27 EP disclosed
US-5312556-A Multifunctional viscosity index improver derived from polyamine containing one primary amine group and at least one tertiary amine group and degraded ethylene copolymer EXXON CHEMICAL PATENTS INC. (US) 1994-05-17 US disclosed
US-5290868-A Ethylene-olefin copolymer grafted with unsaturated carboxylic acid derivative and polyamine EXXON CHEMICAL PATENTS INC. (US) 1994-03-01 US disclosed
US-5290461-A Graft copolymers EXXON CHEMICAL PATENTS INC. (US) 1994-03-01 US disclosed
US-5262075-A Ethylene-olefin copolymer grafted with carboxylic acid and reacted with polyamine, polyol or substituted carboxylic acid component; lubricants EXXON CHEMICAL PATENTS INC. (US) 1993-11-16 US disclosed
US-5252238-A Multifunctional viscosity index improver derived from amido-amine exhibiting improved low temperature viscometric properties EXXON CHEMICAL PATENTS INC. (US) 1993-10-12 US disclosed
US-5244590-A Oil-soluble molecular weight degraded ethylene-alpha-olefin copolymer useful as viscosity modifier for oily compositions; lubricant with improved low temperature viscomeric properties EXXON CHEMICAL PATENTS INC. (US) 1993-09-14 US disclosed
EP-0385729-B1 C14 CARBOXYLATE POLYMER AND VISCOSITY INDEX IMPROVER CONTAINING OLEAGINOUS COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 1993-09-08 EP disclosed
EP-0385729-A2 C14 carboxylate polymer and viscosity index improver containing oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1990-09-05 EP disclosed
EP-0385727-A2 Carboxylate polymer and viscosity index improver containing oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1990-09-05 EP disclosed
EP-0372735-A1 Procédé pour réduire trouble dans des huiles lubrifiantes EXXON CHEMICAL PATENTS INC. (US) 1990-06-13 EP disclosed
US-4900461-A ALPHA-OLEFIN COPOLYMERS AND ASHLESS DISPERSANT; CRYSTAL STRUCTURE, LOW TEMPERATURE PUMPING; LUBRICATING OIL ADDITIVES EXXON CHEMICAL PATENTS INC. (US) 1990-02-13 US disclosed
US-4871523-A HALOGENATED ORGANIC COMPOUNDS; CATALYST FOR OLEFIN COPOLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1989-10-03 US disclosed
US-4804794-A ETHYLENE-ALPHA-OLEFIN COPOLYMER HAVING CRYSTALLIZABLE AND NONCRYSTALLIZABLE SEGMENTS; LUBRICATING OIL ADDITIVES EXXON CHEMICAL PATENTS INC. (US) 1989-02-14 US disclosed
EP-0299608-A1 Improved viscosity modifier polymers EXXON CHEMICAL PATENTS INC. (US) 1989-01-18 EP disclosed
EP-0291359-A2 Vanadium tetrachloride stabilization EXXON CHEMICAL PATENTS INC. (US) 1988-11-17 EP disclosed
EP-0059034-B1 A PROCESS FOR PRODUCING COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-22 EP disclosed
EP-0059034-A1 A process for producing copolymers of ethylene with alpha-olefins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-09-01 EP disclosed