Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15340834 | 1.00 | CA1 (0.52) | CA1CA2ACHECA7CA9 | |
| SCHEMBL15340832 | 1.00 | CA1 (0.52) | CA1CA2ACHECA7CA9 | |
| SCHEMBL1239850 | 0.86 | CA1 (0.45) | CA1CA2ACHECA7CA9 | |
| SCHEMBL9461023 | 0.86 | TP53 (0.55) | CA1CA2ACHECA7CA9 | |
| SCHEMBL9814047 | 0.80 | KDM4E (0.53) | CA1CA2ACHECA7CA9 | |
| Bromide SCHEMBL28922144 | 0.78 | KDM4E (0.51) | CA1CA2ACHECA7CA9 | |
| SCHEMBL14655581 | 0.77 | KDM4E (0.39) | CA1CA2ACHEALDH1A1TDP1 | |
| SCHEMBL13939459 | 0.77 | CA1 (0.55) | CA1CA2ACHECA7CA9 | |
| SCHEMBL7125626 | 0.77 | CA1 (0.55) | CA1CA2ACHECA7CA9 | |
| SCHEMBL21376219 | 0.76 | CA1 (0.48) | CA1CA2ACHECA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387986-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-16 | — | — | US | disclosed |
| EP-0462776-B1 | Preparation of optically active arylaliphatic carboxylic acids | ALBEMARLE CORP (US) | 1995-12-27 | — | — | EP | disclosed |
| EP-0623105-A1 | PREPARATION OF OPTICALLY ACTIVE ALIPHATIC CARBOXYLIC ACIDS. | ALBEMARLE CORP (US) | 1994-11-09 | — | — | EP | disclosed |
| US-5235100-A | PREPARATION OF OPTICALLY ACTIVE ALIPHATIC CARBOXYLIC ACIDS | ETHYL CORPORATION (US) | 1993-08-10 | — | — | US | disclosed |
| WO-1993015039-A1 | PREPARATION OF OPTICALLY ACTIVE ALIPHATIC CARBOXYLIC ACIDS | ETHYL CORPORATION (US) | 1993-08-05 | — | — | WO | disclosed |
| EP-0462776-A2 | Preparation of optically active arylaliphatic carboxylic acids | ALBEMARLE CORPORATION (US) | 1991-12-27 | — | — | EP | disclosed |
| US-5015764-A | Preparation of optically active aliphatic carboxylic acids | ETHYL CORPORATION (US) | 1991-05-14 | — | — | US | disclosed |
| US-4209638-A | RESOLUTION OF ENANTIOMORPHS | THE BOOTS COMPANY LIMITED (GB) | 1980-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387986-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | ITGB1, ITGB2, ITGA2 | CA1 1164/4885CA2 1117/4885ACHE 2032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.