Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255435 | 0.91 | PTGER4 (0.52) | PTGER4TSHRUSP2HTTHSD17B10 | |
| SCHEMBL8863337 | 0.91 | PTGER4 (0.47) | PTGER4 | |
| Hydrochloric Acid SCHEMBL9245428 | 0.90 | PTGER4 (0.47) | PTGER4 | |
| SCHEMBL9255102 | 0.90 | PTGER4 (0.47) | PTGER4 | |
| SCHEMBL9255099 | 0.90 | PTGER4 (0.47) | PTGER4TSHRUSP2HTTHSD17B10 | |
| SCHEMBL9256921 | 0.90 | PTGER4 (0.56) | PTGER4KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9248958 | 0.89 | PTGER4 (0.46) | PTGER4 | |
| SCHEMBL9251533 | 0.89 | PTGER4 (0.51) | PTGER4TSHRUSP2HTTHSD17B10 | |
| SCHEMBL9255240 | 0.89 | PTGER4 (0.55) | PTGER4KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9247706 | 0.89 | PTGER4 (0.46) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |