Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 6/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | RARA | P10276 | 5/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARG | P13631 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795486 | 1.00 | PLA2G4A (0.48) | PLA2G4AGPR52RXRARXRBRXRG | |
| SCHEMBL9251792 | 1.00 | PLA2G4A (0.48) | PLA2G4AGPR52RXRARXRBRXRG | |
| SCHEMBL8795107 | 1.00 | PLA2G4A (0.48) | PLA2G4AGPR52RXRARXRBRXRG | |
| SCHEMBL8795749 | 0.90 | PLA2G4A (0.59) | PLA2G4ARXRARXRBRXRGRARA | |
| SCHEMBL8795289 | 0.90 | PLA2G4A (0.59) | PLA2G4ARXRARXRBRXRGRARA | |
| SCHEMBL9256483 | 0.90 | PLA2G4A (0.59) | PLA2G4ARXRARXRBRXRGRARA | |
| SCHEMBL9256475 | 0.90 | PLA2G4A (0.59) | PLA2G4ARXRARXRBRXRGRARA | |
| SCHEMBL8795020 | 0.89 | PLA2G4A (0.50) | PLA2G4ARXRARXRBRXRGRARA | |
| SCHEMBL9256306 | 0.89 | PLA2G4A (0.50) | PLA2G4ARXRARXRBRXRGRARA | |
| SCHEMBL9256311 | 0.89 | PLA2G4A (0.50) | PLA2G4ARXRARXRBRXRGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | claimed |
| EP-0629604-A2 | Alicyclic phospholipase A2 inhibitors | Bristol-Myers Company (US) | 1994-12-21 | — | — | EP | claimed |