Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598993 | 0.95 | ALOX5 (0.55) | ALOX5ESR2HSD17B3OPRK1 | |
| SCHEMBL2860952 | 0.87 | ALOX5 (0.63) | ALOX5ESR2ESR1MMP3BCL2L1 | |
| SCHEMBL16355701 | 0.81 | ALOX5 (0.50) | ALOX5ESR2HSD17B3OPRK1 | |
| SCHEMBL10456914 | 0.80 | ESR2 (0.54) | ESR2ESR1ABL1ABCB1BCR | |
| SCHEMBL1071089 | 0.80 | ALOX5 (0.61) | ALOX5ESR2ESR1HSD17B3HSD17B10 | |
| Phenol SCHEMBL28213161 | 0.79 | PPARA (0.50) | HSD17B10BCL2L1PPARA | |
| SCHEMBL1426624 | 0.78 | EGFR (0.60) | ALOX5HSD17B3HSD17B10 | |
| SCHEMBL2863552 | 0.77 | ALOX5 (0.65) | ALOX5ESR2ESR1HSD17B10MMP3 | |
| SCHEMBL28600186 | 0.77 | ALOX5 (0.55) | ALOX5ESR2ESR1HSD17B3MMP3 | |
| SCHEMBL10455047 | 0.77 | ESR1 (0.67) | ESR2ESR1MMP3BCL2L1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235025-A | Cross-linkable thermotropic liquid crystalline aromatic polyester | HIMONT ITALIA S.R.L. (IT) | 1993-08-10 | — | — | US | claimed |
| US-4923955-A | Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene | MONTEDISON S.P.A. (IT) | 1990-05-08 | — | — | US | claimed |
| EP-0321107-B1 | Thermotropic liquid-crystalline aromatic polyesters | HIMONT ITALIA (IT) | 1995-01-25 | — | — | EP | disclosed |
| EP-0293908-B1 | Molding material for optics | MITSUBISHI GAS CHEMICAL CO (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-5235025-A | Cross-linkable thermotropic liquid crystalline aromatic polyester | HIMONT ITALIA S.R.L. (IT) | 1993-08-10 | — | — | US | disclosed |
| EP-0383177-A2 | Cross-linkable thermotropic liquid crystalline aromatic polyesters | HIMONT ITALIA S.r.l. (IT) | 1990-08-22 | — | — | EP | disclosed |
| US-4923955-A | Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene | MONTEDISON S.P.A. (IT) | 1990-05-08 | — | — | US | disclosed |
| US-4888401-A | GRAFT POLYMERS OF STYRENE WITH MALEIC ANHYDRIDE OR MALEIMIDE AND AROMATIC POLYCARBONATES | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 1989-12-19 | — | — | US | disclosed |
| EP-0321107-A1 | Thermotropic liquid-crystalline aromatic polyesters | HIMONT ITALIA S.r.l. (IT) | 1989-06-21 | — | — | EP | disclosed |