Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30067652 | 0.81 | ALDH1A1 (0.32) | TDP1LMNAAPP | |
| SCHEMBL9254176 | 0.81 | ALDH1A1 (0.32) | TDP1LMNAAPP | |
| SCHEMBL13685018 | 0.78 | ALDH1A1 (0.33) | TDP1 | |
| SCHEMBL27134316 | 0.76 | POLB (0.43) | POLBAPEX1TDP1 | |
| SCHEMBL7862601 | 0.76 | — | — | |
| SCHEMBL2543510 | 0.75 | POLB (0.38) | POLBAPEX1TDP1 | |
| SCHEMBL12546419 | 0.71 | ALDH1A1 (0.33) | TDP1 | |
| SCHEMBL3945319 | 0.67 | — | — | |
| SCHEMBL20171668 | 0.67 | — | — | |
| SCHEMBL15084287 | 0.65 | POLB (0.39) | POLBAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422365-A | Hydroxy, ether, and/or acyloxy substituted, saturated or partially unsaturated naphthalenes; for controlling insulin secretion | ADIR ET COMPAGNIE (FR) | 1995-06-06 | — | — | US | claimed |
| US-5422365-A | Hydroxy, ether, and/or acyloxy substituted, saturated or partially unsaturated naphthalenes; for controlling insulin secretion | ADIR ET COMPAGNIE (FR) | 1995-06-06 | — | — | US | disclosed |