Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9252872 | 0.99 | KDM4E (0.60) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9257131 | 0.86 | KDM4E (0.58) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| Hydrochloric Acid SCHEMBL9876458 | 0.85 | KDM4E (0.57) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9247077 | 0.81 | KDM4E (0.62) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL10423391 | 0.80 | KDM4E (0.61) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9250192 | 0.79 | KDM4E (0.60) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| Hydrochloric Acid SCHEMBL10334149 | 0.78 | KDM4E (0.75) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL13204390 | 0.76 | KDM4E (0.63) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9249919 | 0.75 | GAA (0.61) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL10423390 | 0.75 | KDM4E (0.65) | KDM4EMEN1KMT2ACYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446146-A | Treatment of liver disorders | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |