Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247077 | 0.87 | KDM4E (0.62) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9257131 | 0.86 | KDM4E (0.58) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| Hydrochloric Acid SCHEMBL9876458 | 0.85 | KDM4E (0.57) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9250192 | 0.84 | KDM4E (0.60) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| Hydrochloric Acid SCHEMBL10334149 | 0.83 | KDM4E (0.75) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL10423390 | 0.81 | KDM4E (0.65) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL9252263 | 0.80 | KDM4E (0.61) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| Hydrochloric Acid SCHEMBL9252872 | 0.79 | KDM4E (0.60) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL15303789 | 0.79 | KDM4E (0.83) | KDM4EMEN1KMT2ACYP2C9ALOX15 | |
| SCHEMBL25834338 | 0.79 | KDM4E (0.69) | KDM4EMEN1KMT2ACYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2028172-A | — | — | None | — | — | JP | disclosed |
| JP-H0228172-A | REMEDY FOR LIVER DISEASE AND PIPERAZINE DERIVATIVE | NIPPON CHEMIPHAR CO LTD | 1990-01-30 | — | — | JP | disclosed |