Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GCG | P01275 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251550 | 0.92 | SIRT2 (0.52) | KMT2AMEN1MAPTTP53SIRT2 | |
| SCHEMBL9247672 | 0.90 | KMT2A (0.49) | KMT2AMEN1MAPTTP53SIRT2 | |
| SCHEMBL9251899 | 0.89 | HPGD (0.49) | KMT2AMEN1MAPTTP53SIRT2 | |
| SCHEMBL9254349 | 0.86 | ATM (0.58) | KMT2AMEN1MAPTTP53SIRT2 | |
| SCHEMBL9255544 | 0.85 | F10 (0.46) | KMT2AMEN1MAPTTP53GCGR | |
| SCHEMBL9251354 | 0.83 | SIRT2 (0.53) | KMT2AMEN1MAPTTP53SIRT2 | |
| SCHEMBL9256809 | 0.83 | ATM (0.47) | KMT2AMEN1MAPTTP53SIRT2 | |
| SCHEMBL9249490 | 0.83 | HDAC1 (0.56) | ITGB3ITGA2B | |
| SCHEMBL9255152 | 0.82 | ATM (0.46) | KMT2AMEN1MAPTTP53SIRT2 | |
| SCHEMBL9255433 | 0.82 | JAK2 (0.50) | RIPK2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |