Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 7/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233145 | 0.91 | NPSR1 (0.53) | NPSR1F10PTPN1NR1D1HDAC8 | |
| SCHEMBL29727828 | 0.91 | NPSR1 (0.53) | NPSR1F10PTPN1NR1D1HDAC8 | |
| SCHEMBL1049445 | 0.88 | NPSR1 (0.63) | NPSR1F10PTPN1NR1D1HDAC8 | |
| SCHEMBL9591709 | 0.87 | NPSR1 (0.59) | NPSR1F10PTPN1HDAC8PREP | |
| SCHEMBL1052393 | 0.85 | NPSR1 (0.62) | NPSR1F10PTPN1ACE | |
| SCHEMBL30314166 | 0.85 | NPSR1 (0.62) | NPSR1F10PTPN1ACE | |
| SCHEMBL14862925 | 0.85 | NPSR1 (0.62) | NPSR1F10PTPN1ACE | |
| SCHEMBL3629346 | 0.85 | NPSR1 (0.62) | NPSR1F10PTPN1ACE | |
| SCHEMBL29401156 | 0.85 | NPSR1 (0.62) | NPSR1F10PTPN1ACE | |
| SCHEMBL30547966 | 0.85 | PREP (0.54) | NPSR1F10PTPN1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401766-A | Hypotensive agents with vasodilation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| US-5162362-A | Hypotensive agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5158959-A | Treatment of hypertension | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |