Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727828 | 1.00 | NPSR1 (0.53) | NPSR1NR1D1PTPN1HDAC8F10 | |
| SCHEMBL9252347 | 0.91 | NPSR1 (0.58) | NPSR1NR1D1PTPN1HDAC8F10 | |
| SCHEMBL20143637 | 0.88 | PTPN1 (0.50) | NPSR1PTPN1HDAC8 | |
| SCHEMBL17486403 | 0.88 | PTPN1 (0.50) | NPSR1PTPN1HDAC8 | |
| SCHEMBL7228628 | 0.87 | ACE (0.59) | NPSR1PTPN1HDAC8FKBP1A | |
| SCHEMBL7228636 | 0.87 | ACE (0.59) | NPSR1PTPN1HDAC8FKBP1A | |
| SCHEMBL204506 | 0.87 | FKBP1A (0.49) | PTPN1FKBP1A | |
| SCHEMBL204505 | 0.87 | FKBP1A (0.49) | PTPN1FKBP1A | |
| SCHEMBL6787776 | 0.87 | FKBP1A (0.49) | PTPN1FKBP1A | |
| SCHEMBL4480030 | 0.87 | NR1D1 (0.61) | NR1D1PTPN1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309014-A1 | PROCESS FOR PREPARATION OF ICATIBANT ACETATE | EMCURE PHARMACEUTICALS LIMITED (IN) | 2019-10-10 | — | — | US | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190309014-A1 | PROCESS FOR PREPARATION OF ICATIBANT ACETATE | VIP, HM13, C5AR2 | NPSR1 2236/4885NR1D1 4755/4885PTPN1 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.