Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209772 | 0.90 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9256165 | 0.88 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9212533 | 0.86 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9209013 | 0.85 | ALOX5 (0.81) | ALOX5 | |
| SCHEMBL9223136 | 0.82 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9227643 | 0.80 | ALOX5 (0.57) | ALOX5 | |
| Zd-2138 SCHEMBL1083603 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9135113 | 0.78 | ALOX5 (0.80) | ALOX5 | |
| Zd-2138 SCHEMBL29372755 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9139351 | 0.77 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401751-A | Enzyme inhibitors for 5-lipoxygenase | ZENECA LIMITED (GB) | 1995-03-28 | — | — | US | disclosed |
| US-5236919-A | Inhibitorsof enzyme 5-lipoxygenase | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-17 | — | — | US | disclosed |
| US-5134148-A | Heterocycles for use as inhibitors of leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-28 | — | — | US | disclosed |
| EP-0385662-A2 | Heterocycles with inhibitory activity of 5-lipoxygenase | ZENECA LIMITED (GB) | 1990-09-05 | — | — | EP | disclosed |