Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255678 | 1.00 | ALOX5 (0.42) | ALOX5EPHX2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9260680 | 0.80 | ALOX5 (0.56) | ALOX5EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9260118 | 0.80 | ALOX5 (0.56) | ALOX5EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9285681 | 0.75 | ALOX5 (0.46) | ALOX5EPHX2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9285478 | 0.75 | ALOX5 (0.46) | ALOX5EPHX2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9025062 | 0.75 | ALOX5 (0.56) | ALOX5EPHX2ALDH1A1GAA | |
| SCHEMBL9262607 | 0.74 | ALOX5 (0.44) | ALOX5EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9091224 | 0.72 | ALOX5 (0.55) | ALOX5EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9091217 | 0.72 | ALOX5 (0.55) | ALOX5EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9257237 | 0.70 | ALOX5 (0.42) | ALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030671-A1 | SUBSTITUTED ARYL- AND HETEROARYLALKENYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-11-16 | — | — | WO | claimed |
| WO-1995030671-A1 | SUBSTITUTED ARYL- AND HETEROARYLALKENYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-11-16 | — | — | WO | disclosed |