Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189390 | 1.00 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL5789042 | 0.85 | PLG (0.53) | MAPTMEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL8991774 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL688602 | 0.85 | PLG (0.53) | MAPTMEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL8991772 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11075182 | 0.84 | PLG (0.52) | MAPTMEN1KMT2AALDH1A1HSD11B1 | |
| SCHEMBL10479615 | 0.84 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1414272 | 0.84 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10479620 | 0.84 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL1068668 | 0.84 | PLG (0.52) | MAPTMEN1KMT2AALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |
| US-4387102-A | 4-(N-(3',4'-Methylenedioxybenzylidene)-aminomethyl)cyclohexane-1-carboxylic acid and derivatives thereof and pharmaceutical composition thereof | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-06-07 | — | — | US | disclosed |