Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252741 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1TSHRMAPK1UBE2N | |
| SCHEMBL9252019 | 0.82 | KDM4E (0.53) | SMN1; SMN2TSHRACHEKDM4EALDH1A1 | |
| SCHEMBL9015425 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1TSHRKDM4EALDH1A1 | |
| SCHEMBL9015429 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1TSHRKDM4EALDH1A1 | |
| SCHEMBL9248939 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2TSHRKDM4EALDH1A1TP53 | |
| SCHEMBL9248944 | 0.78 | ALDH1A1 (0.54) | SMN1; SMN2TSHRKDM4EALDH1A1TP53 | |
| SCHEMBL705489 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL705490 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL14341897 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1TSHRMAPK1UBE2N | |
| SCHEMBL30995620 | 0.71 | CA12 (0.49) | SMN1; SMN2NPC1TSHRACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472979-A | Antithrombotics | ADIR ET COMPAGNIE (FR) | 1995-12-05 | — | — | US | disclosed |