Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246633 | 0.96 | TYMS (0.71) | TYMS | |
| SCHEMBL9255447 | 0.95 | TYMS (0.73) | TYMS | |
| SCHEMBL9249203 | 0.94 | TYMS (0.67) | TYMS | |
| SCHEMBL9281162 | 0.93 | TYMS (0.66) | TYMS | |
| SCHEMBL9088375 | 0.92 | TYMS (0.79) | TYMS | |
| SCHEMBL9556241 | 0.90 | TYMS (0.70) | TYMS | |
| SCHEMBL9247891 | 0.90 | DHFR (0.68) | — | |
| SCHEMBL9255122 | 0.90 | TYMS (0.63) | TYMS | |
| SCHEMBL9808475 | 0.89 | TYMS (0.69) | TYMS | |
| SCHEMBL9808308 | 0.89 | TYMS (0.69) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395838-A | Aromatic aminomethyl substitutes compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| US-5252573-A | Quinazoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-12 | — | — | US | disclosed |
| US-5089499-A | Anticarcinogenic agents; thymidylate synthetase inhibitors; antiallergens; psoriasis | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |