Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.61 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.49 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorzoxazone SCHEMBL35177 | 0.84 | KDM4E (0.70) | PSMB8KDM4EXDHMAPTRAB9A | |
| SCHEMBL27555535 | 0.83 | SNCA (0.56) | PIK3CGSNCAPSMB8PSMB5KDM4E | |
| Chlorzoxazone SCHEMBL27696905 | 0.81 | KDM4E (0.66) | PSMB8KDM4EMAPTRAB9ALMNA | |
| SCHEMBL895172 | 0.79 | PIK3CG (0.66) | PIK3CGSNCAPSMB8PSMB5KDM4E | |
| SCHEMBL17265862 | 0.79 | ESR1 (0.61) | KDM4EMAPTRAB9ALMNAALOX15 | |
| SCHEMBL29999385 | 0.79 | ESR1 (0.61) | KDM4EMAPTRAB9ALMNAALOX15 | |
| SCHEMBL31334714 | 0.76 | DAGLA (0.42) | SNCARAB9AALOX15STSESR1 | |
| SCHEMBL19086925 | 0.76 | PIK3CG (0.61) | PIK3CGSNCAPSMB8PSMB5KDM4E | |
| SCHEMBL2056293 | 0.76 | PIK3CG (0.61) | PIK3CGSNCAPSMB8PSMB5KDM4E | |
| SCHEMBL3062851 | 0.76 | PIK3CG (0.61) | PIK3CGSNCAPSMB8PSMB5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003710-A | Preparation method of 2-mercapto-6-chlorobenzoxazole | 镇江先锋植保科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-117003710-A | Preparation method of 2-mercapto-6-chlorobenzoxazole | 镇江先锋植保科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-117003710-A | Preparation method of 2-mercapto-6-chlorobenzoxazole | 镇江先锋植保科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116082223-A | Carbamate compound and preparation method and application thereof | 北京亦农生物科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2017213137-A1 | NOVEL COMPOUND AND AGRICULTURAL/HORTICULTURAL CHEMICAL USING SAME AS ACTIVE INGREDIENT | アグロカネショウ株式会社 | 2017-12-14 | — | — | WO | disclosed |
| US-5405867-A | Milbemycin derivatives with insecticidal and anthelmintic properties; for plants and animals | SANKYO COMPANY, LIMITED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0342710-B1 | MACROLIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4963582-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO COMPANY LIMITED (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0342710-A1 | Macrolide compounds, their preparation and their use | Sankyo Company Limited (JP) | 1989-11-23 | — | — | EP | disclosed |
| EP-0246739-A2 | Macrolide compounds, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1987-11-25 | — | — | EP | disclosed |