SCHEMBL895172

SCHEMBL895172

Clc1ccc2nc(Cl)oc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.66
PSMB8 P28062 2/20 0.59
PSMB5 P28074 1/20 0.59
S1PR3 Q99500 7/20 0.51
SNCA P37840 1/20 0.47
SOS1 Q07889 1/20 0.46
FBP1 P09467 1/20 0.46
MAPT P10636 2/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
THRB P10828 1/20 0.46
ALOX15 P16050 1/20 0.46
MAPK1 P28482 1/20 0.46
XDH P47989 2/20 0.44
NLRP3 Q96P20 2/20 0.44
RAB9A P51151 2/20 0.43
S1PR1 P21453 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
CASP3 P42574 1/20 0.41
SENP7 Q9BQF6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL28460791 0.89 PIK3CG (0.54) PIK3CGPSMB8PSMB5S1PR3SNCA
Toluene SCHEMBL28153021 0.86 PIK3CG (0.51) PIK3CGPSMB8PSMB5S1PR3SNCA
SCHEMBL1672481 0.83 LMNA (0.66) PIK3CGPSMB8FBP1MAPTLMNA
SCHEMBL24550537 0.80 AHR (0.51) PIK3CGPSMB8PSMB5S1PR3MAPT
SCHEMBL24552412 0.80 AHR (0.51) PIK3CGPSMB8PSMB5S1PR3MAPT
SCHEMBL9896463 0.79 PIK3CG (1.00) PIK3CGPSMB8PSMB5S1PR3SNCA
SCHEMBL3062851 0.79 PIK3CG (0.61) PIK3CGPSMB8PSMB5S1PR3SNCA
SCHEMBL9252784 0.79 PIK3CG (0.61) PIK3CGPSMB8PSMB5S1PR3SNCA
SCHEMBL9252792 0.79 PIK3CG (0.61) PIK3CGPSMB8PSMB5S1PR3SNCA
SCHEMBL19086925 0.79 PIK3CG (0.61) PIK3CGPSMB8PSMB5S1PR3SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118638073-B Oxazoyl grass method for synthesizing amine 苏州开元民生科技股份有限公司 2024-12-24 CN claimed
CN-118638073-A Oxazoyl grass method for synthesizing amine 苏州开元民生科技股份有限公司 2024-09-13 CN claimed
CN-113717123-B Preparation method of metamifop 内蒙古蓝科生物科技有限公司 2023-10-10 CN claimed
CN-113620898-B Synthesis method of oxazoxamide 江苏富鼎化学有限公司 2023-07-25 CN claimed
CN-109761928-B Preparation method of 2, 6-dichlorobenzoxazole 安徽丰乐农化有限责任公司 2023-06-23 CN claimed
CN-111732553-B Method for synthesizing herbicide fenoxaprop-p-ethyl 江苏富鼎化学有限公司 2022-08-05 CN claimed
CN-114276312-A Synthetic method of high-purity metamifop 天富凯业(辽宁)新材料有限公司 2022-04-05 CN claimed
CN-109553588-B Synthetic method of 2,6-dichlorobenzoxazole 江苏中旗科技股份有限公司 2022-03-25 CN claimed
CN-216093629-U Preparation 2,6 catalytic reaction cauldron for dichloro benzoxazole 抚州市萨弗隆化工有限公司 2022-03-22 CN claimed
CN-215277966-U Centrifuge is used in production of 2,6 dichloro benzoxazole 抚州市萨弗隆化工有限公司 2021-12-24 CN claimed
US-4935522-A Process for producing ethyl 2-[4'-(6\"-chloro-2\"-benzoxazolyloxy)phenoxy]propionate HOECHST CELANESE CORPORATION (US) 1990-06-19 US claimed
EP-0334597-A1 A process for producing ethyl 2-(4'-(6\"-chloro-2\"-benzox-azolyl) phenoxy) proprionate HOECHST CELANESE CORPORATION (US) 1989-09-27 EP claimed
US-4714766-A Process for the preparation of 2-chlorobenzoxazoles CASSELLA AKTIENGESELLSCHAFT (DE) 1987-12-22 US claimed
EP-0141053-B1 METHOD FOR THE PREPARATION OF 2-CHLORBENZOXAZOLES CASSELLA Aktiengesellschaft (DE) 1987-08-19 EP claimed
US-4658034-A Process for the preparation of 2,6-dichlorobenzoxazole HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-14 US claimed
EP-0153656-A1 Method for the preparation of 2,6-dichlorobenzoxazole HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-04 EP claimed
EP-0141053-A1 Method for the preparation of 2-chlorbenzoxazoles CASSELLA Aktiengesellschaft (DE) 1985-05-15 EP claimed
US-4433153-A Process for the manufacture of 2,6-dichlorobenzoxazole and 2,6-dichlorobenzthiazole HOECHST AKTIENGESELLSCHAFT (DE) 1984-02-21 US claimed
EP-0043573-B1 PROCESS FOR THE PREPARATION OF 2,6-DICHLOROBENZOXAZOLE OR 2,6-DICHLOROBENZTHIAZOLE HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-31 EP claimed
EP-0043573-A1 Process for the preparation of 2,6-dichlorobenzoxazole or 2,6-dichlorobenzthiazole HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-13 EP claimed