Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | ATF4 | P18848 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252822 | 1.00 | PARP15 (0.38) | PARP15PARP10PARP2ATF4LTA4H | |
| SCHEMBL9252833 | 1.00 | PARP15 (0.38) | PARP15PARP10PARP2ATF4LTA4H | |
| SCHEMBL9249242 | 0.92 | PARP15 (0.39) | PARP15PARP10PARP2ATF4LTA4H | |
| SCHEMBL9249223 | 0.92 | PARP15 (0.39) | PARP15PARP10PARP2ATF4LTA4H | |
| SCHEMBL9249250 | 0.92 | PARP15 (0.39) | PARP15PARP10PARP2ATF4LTA4H | |
| SCHEMBL9253221 | 0.87 | DRD4 (0.39) | PARP15PARP10PARP2 | |
| SCHEMBL9253229 | 0.87 | DRD4 (0.39) | PARP15PARP10PARP2 | |
| SCHEMBL9253212 | 0.87 | DRD4 (0.39) | PARP15PARP10PARP2 | |
| SCHEMBL9252109 | 0.86 | TRPV4 (0.38) | PARP15PARP10 | |
| SCHEMBL9252101 | 0.86 | TRPV4 (0.38) | PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-5013477-A | Alkenylbicyclohexane liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |