Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 12/20 | 0.51 |
| ▸ | BCHE | P06276 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256559 | 1.00 | MAPT (0.56) | MAPTACHEBCHEALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9256019 | 0.99 | MAPT (0.55) | MAPTACHEBCHE | |
| SCHEMBL9255203 | 0.90 | ACHE (0.56) | MAPTACHEALDH1A1 | |
| SCHEMBL9260059 | 0.88 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL9255981 | 0.88 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL9256157 | 0.88 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL9255193 | 0.88 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL9252756 | 0.85 | ACHE (0.51) | MAPTACHEBCHEALDH1A1POLB | |
| SCHEMBL10699056 | 0.83 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL9260330 | 0.81 | ACHE (0.74) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |