Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15125814 | 0.78 | — | — | |
| SCHEMBL9442121 | 0.67 | — | — | |
| SCHEMBL23824904 | 0.62 | CYP19A1 (0.41) | LMNABLMKDM4ENPC1ALDH1A1 | |
| SCHEMBL19871625 | 0.61 | CYP3A4 (0.35) | TDP1LMNABLMALDH1A1CYP3A4 | |
| SCHEMBL10066554 | 0.61 | TDP1 (0.33) | TDP1LMNABLMALDH1A1CYP2A6 | |
| SCHEMBL8903319 | 0.61 | TDP1 (0.33) | TDP1LMNABLMALDH1A1CYP2A6 | |
| SCHEMBL819351 | 0.61 | TSHR (0.35) | TDP1CA12CA2CA4CA14 | |
| Naphthalene SCHEMBL30426987 | 0.59 | CYP2A6 (0.57) | TDP1CA2LMNABLMKDM4E | |
| SCHEMBL26071 | 0.59 | — | — | |
| Naphthalene SCHEMBL20578253 | 0.59 | CYP2A6 (0.57) | TDP1CA2LMNABLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317082-B | A kind of Rufloxacin (rhodanine beta-unsaturated ketone) amide derivatives and its preparation method and application | 河南大学 | 2018-08-31 | — | — | CN | claimed |
| JP-2242816-A | — | — | None | — | — | JP | disclosed |
| CN-103936709-B | Synthetic method of piperonal | 李东风 | 2017-01-18 | — | — | CN | disclosed |
| US-5432237-A | Radically polymerizable composition | SHOWA DENKO K.K. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0399463-B1 | Radically polymerizable composition | SHOWA DENKO KK (JP) | 1994-02-23 | — | — | EP | disclosed |
| CN-1022691-C | Composition of free redical polymerization | SHOWA DENKO KK (JP) | 1993-11-10 | — | — | CN | disclosed |
| CN-1047515-A | The composition of free redical polymerization | SHOWA DENKO KK (JP) | 1990-12-05 | — | — | CN | disclosed |
| EP-0399463-A2 | Radically polymerizable composition | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-11-28 | — | — | EP | disclosed |
| JP-H02242816-A | POLYMER HAVING ISOTHIANAPHTHENE STRUCTURE AND PRODUCTION THEREOF | SHOWA DENKO KK | 1990-09-27 | — | — | JP | disclosed |
| US-4505800-A | Sodium-selective compositions and electrodes containing same | EASTMAN KODAK COMPANY (US) | 1985-03-19 | — | — | US | disclosed |