SCHEMBL819351

SCHEMBL819351

CC=c1ccccc1=CC

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
LMNA P02545 3/20 0.35
ACHE P22303 2/20 0.35
ALOX12 P18054 2/20 0.33
CYP2A6 P11509 1/20 0.31
CYP1A2 P05177 1/20 0.30
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18387086 1.00 TSHR (0.35) TSHRLMNAACHEALOX12CYP2A6
SCHEMBL23350320 0.85
SCHEMBL12993101 0.85
SCHEMBL8759821 0.83 TSHR (0.30) TSHRACHE
SCHEMBL23430361 0.83 MAP2K7 (0.31) CYP1A2
SCHEMBL15744245 0.81 ALDH1A1 (0.31) TSHR
SCHEMBL19040648 0.81 TSHR (0.31) TSHR
SCHEMBL24088132 0.81 LMNA (0.32) TSHRLMNACYP2A6MEN1THRB
SCHEMBL20961675 0.81 ALDH1A1 (0.36) TSHR
SCHEMBL18909699 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115445582-A Hydrophobic modified molecular sieve and preparation method and application thereof 国网河北能源技术服务有限公司 2022-12-09 CN claimed
CN-101410438-B Low VOC epoxy silane oligomer and compositions containing same MOMENTIVE PERFORMANCE MAT INC 2013-07-10 CN claimed
CN-101180334-B Crosslinkable silane-terminated polymers and sealant compositions made therewith MOMENTIVE PERFORMANCE MAT INC (US) 2012-04-04 CN claimed
CN-101124274-B Filler treatments utilizing low VOC silanes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-12-21 CN claimed
CN-101910185-A Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MAT INC 2010-12-08 CN claimed
CN-101410438-A Low VOC epoxy silane oligomer and compositions containing same MOMENTIVE PERFORMANCE MAT INC (US) 2009-04-15 CN claimed
CN-101180334-A Crosslinkable silane-terminated polymers and sealant compositions made therewith MOMENTIVE PERFORMANCE MAT INC (US) 2008-05-14 CN claimed
CN-101124175-A Sizing compositions for fibers utilizing low VOC silanes MOMENTIVE PERFORMANCE MAT INC (US) 2008-02-13 CN claimed
CN-101124274-A Filler treatments utilizing low VOC silanes MOMENTIVE PERFORMANCE MAT INC (US) 2008-02-13 CN claimed
US-3966711-A 4-Alkyl-1,4-diaza-5-oxo-cycloheptanes and their 1-oxyls CIBA-GEIGY CORPORATION (US) 1976-06-29 US claimed
WO-2024017471-A1 DEFOAMING COMPOSITIONS FOR DETERGENTS WACKER CHEMIE AG (DE) 2024-01-25 WO disclosed
CN-115445582-A Hydrophobic modified molecular sieve and preparation method and application thereof 国网河北能源技术服务有限公司 2022-12-09 CN disclosed
CN-109999905-B Preparation and application of high-selectivity hydrosilylation catalyst 北京深云智合科技有限公司 2021-08-20 CN disclosed
CN-108473789-A The wet structure of surface modified calcium carbonate is handled OMYA国际股份公司 2018-08-31 CN disclosed
CN-101910185-B Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MAT INC 2014-04-30 CN disclosed
US-5139955-A Reactive base, sulfur dioxide, iodide, conducting salt dissolved in alcoholic solvent; membrane-free cell RIEDEL-DE HAEN AG (DE) 1992-08-18 US disclosed
CN-1047679-A NOVEL DAMPING COMPOSITIONS ROHM & HAAS (US) 1990-12-12 CN disclosed
EP-0384195-A2 Reagent for coulometrically determining water capacity RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1990-08-29 EP disclosed
US-3971757-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1976-07-27 US disclosed
US-3966711-A 4-Alkyl-1,4-diaza-5-oxo-cycloheptanes and their 1-oxyls CIBA-GEIGY CORPORATION (US) 1976-06-29 US disclosed