Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 6/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546800 | 1.00 | CACNA1C (0.50) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL9287154 | 0.91 | ADORA3 (0.55) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7544621 | 0.85 | CACNA1C (0.54) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7554839 | 0.84 | CACNA1C (0.53) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7402137 | 0.83 | CACNA1C (0.53) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7540434 | 0.82 | CACNA1C (0.52) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7365768 | 0.81 | KDM4E (0.51) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7446056 | 0.80 | CYP2C9 (0.54) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7443841 | 0.80 | CYP2C9 (0.54) | CACNA1CADORA3CACNA1FCACNA1DCACNA1S | |
| SCHEMBL17371182 | 0.79 | KDM4E (0.60) | ADORA3GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378718-A | Cardiovascular activity, hypotensive | CEDONA PHARMACEUTICALS B.V. (NL) | 1995-01-03 | — | — | US | disclosed |