Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246403 | 0.85 | MGLL (0.39) | PHGDHMGLLPOLBALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL9254069 | 0.83 | MGLL (0.38) | PHGDHMGLLALDH1A1CA1CA2 | |
| SCHEMBL9253056 | 0.77 | CA1 (0.32) | PHGDHMGLLPOLBALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9258749 | 0.76 | CA1 (0.32) | PHGDHMGLLPOLBALDH1A1MEN1 | |
| SCHEMBL10474882 | 0.75 | GAA (0.44) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9256748 | 0.73 | CYP2C19 (0.49) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9253273 | 0.73 | KMT2A (0.41) | POLBALDH1A1MEN1KMT2ACA1 | |
| Hydrochloric Acid SCHEMBL9255254 | 0.73 | CYP2C19 (0.48) | POLBALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9249919 | 0.72 | GAA (0.61) | PHGDHMGLLPOLBALDH1A1MEN1 | |
| SCHEMBL9257131 | 0.72 | KDM4E (0.58) | POLBALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446146-A | Treatment of liver disorders | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0326379-B1 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5070089-A | INHIBITION OF LIPID PEROXIDATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0326379-A2 | Therapeutic agent for liver disease and piperazine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |