Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.55 |
| ▸ | DRD2 | P14416 | 6/20 | 0.55 |
| ▸ | PTAFR | P25105 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253469 | 1.00 | DRD3 (0.55) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9253460 | 1.00 | DRD3 (0.55) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9668939 | 0.95 | PTAFR (0.52) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9668934 | 0.95 | PTAFR (0.52) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9668942 | 0.95 | PTAFR (0.52) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9669731 | 0.95 | PTAFR (0.59) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9669732 | 0.95 | PTAFR (0.59) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9258675 | 0.93 | PTAFR (0.59) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9258677 | 0.93 | PTAFR (0.59) | DRD3DRD2PTAFRKDM4EALDH1A1 | |
| SCHEMBL9668558 | 0.90 | PTAFR (0.56) | DRD3DRD2PTAFRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |