Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 12/20 | 0.55 |
| ▸ | DRD3 | P35462 | 12/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258677 | 1.00 | PTAFR (0.59) | PTAFRDRD2DRD3ALOX5KDM4E | |
| SCHEMBL9669732 | 0.97 | PTAFR (0.59) | PTAFRDRD2DRD3ALOX5KDM4E | |
| SCHEMBL9669731 | 0.97 | PTAFR (0.59) | PTAFRDRD2DRD3ALOX5KDM4E | |
| SCHEMBL9668558 | 0.94 | PTAFR (0.56) | PTAFRDRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL9668562 | 0.94 | PTAFR (0.56) | PTAFRDRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL9253464 | 0.93 | DRD3 (0.55) | PTAFRDRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL9253469 | 0.93 | DRD3 (0.55) | PTAFRDRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL9253460 | 0.93 | DRD3 (0.55) | PTAFRDRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL9253997 | 0.93 | PTAFR (0.52) | PTAFRDRD2DRD3ALOX5KDM4E | |
| SCHEMBL9253986 | 0.93 | PTAFR (0.52) | PTAFRDRD2DRD3ALOX5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |