⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705379 | 0.66 | KDM4E (0.37) | — | |
| SCHEMBL3261593 | 0.62 | TLR8 (0.42) | — | |
| SCHEMBL23071486 | 0.58 | — | — | |
| SCHEMBL17731606 | 0.57 | KDM4E (0.50) | — | |
| SCHEMBL23071507 | 0.56 | — | — | |
| SCHEMBL23071462 | 0.55 | LMNA (0.30) | — | |
| SCHEMBL23761187 | 0.55 | — | — | |
| SCHEMBL17731496 | 0.55 | BACE1 (0.36) | — | |
| SCHEMBL10705266 | 0.53 | — | — | |
| SCHEMBL15598293 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425283-B1 | Novel triazolyl hydrazide derivatives and process for their preparation | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1995-05-10 | — | — | EP | disclosed |
| US-5225410-A | Antiangina, antiulcer agents | EGIS GYOGYSZERGYAR (HU) | 1993-07-06 | — | — | US | disclosed |
| EP-0425283-A2 | Novel triazolyl hydrazide derivatives and process for their preparation | EGIS GYOGYSZERGYAR (HU) | 1991-05-02 | — | — | EP | disclosed |